What is Itraconazole?
Itraconazole is an antifungal medication that fights infections caused by fungus.
Itraconazole is used to treat infections in adults caused by fungus, which can invade any part of the body including the lungs, mouth or throat, toenails, or fingernails.
It is not known if Itraconazole is safe and effective in children.
You should not take Itraconazole if you have ever had heart failure.
If you have liver or kidney disease, you should not take Itraconazole with colchicine, fesoterodine, or solifenacin.
Itraconazole may harm an unborn baby. Avoid getting pregnant while taking itraconazole and for 2 months after your last dose.
Stop using Itraconazole and call your doctor at once if you have signs of congestive heart failure: feeling tired or short of breath, cough with mucus, fast heartbeats, swelling, rapid weight gain, or sleep problems.
Life-threatening side effects may occur if you take itraconazole with certain other drugs. Tell your doctor about all your current medicines and any you start or stop using.
Many drugs can interact with itraconazole, and some drugs should not be used together. This includes prescription and over-the-counter medicines, vitamins, and herbal products. Tell your doctor about all medicines you use, and those you start or stop using during your treatment with Itraconazole.
Before taking this medicine
You should not take Itraconazole if you are allergic to itraconazole or similar medicines such as fluconazole or ketoconazole, or if you have ever had congestive heart failure.
Life-threatening side effects may occur if you take Itraconazole with certain other drugs. Your doctor may change your treatment plan if you have used other medicines in the past 2 weeks, especially:
- lurasidone or pimozide (anti-psychotic medications);
- lomitapide, lovastatin, simvastatin (cholesterol-lowering medicines);
- dihydroergotamine, ergonovine, ergotamine, or methylergonovine (ergot medicines);
- eplerenone, felodipine, ivabradine, or nisoldipine (heart or blood pressure medicines);
- disopyramide, dofetilide, dronedarone, or quinidine (medicines for heart rhythm disorders); or
- oral midazolam, or triazolam (Valium-like sedatives).
If you have liver or kidney disease, you should not take Itraconazole with colchicine, fesoterodine, solifenacin, or telithromycin.
Itraconazole may harm an unborn baby. Use effective birth control to prevent pregnancy while you are using this medicine and for at least 2 months after your last dose. Tell your doctor if you become pregnant.
How should I take Itraconazole?
Take Itraconazole exactly as prescribed by your doctor. Follow all directions on your prescription label and read all medication guides or instruction sheets.
Do not share this medicine with another person, even if they have the same symptoms you have.
The Itraconazole capsule should be taken with food.
Swallow the capsule whole and do not crush, chew, break, or open it.
Take the oral solution (liquid) on an empty stomach, at least 1 hour before or 2 hours after a meal. Swish the liquid in your mouth for several seconds before swallowing it.
Measure liquid medicine carefully. Use the dosing syringe provided, or use a medicine dose-measuring device (not a kitchen spoon).
The Itraconazole PulsePak has a special dosing schedule that includes not taking the medicine for several days in a row. Follow all dosing instructions carefully.
Itraconazole capsules should not be used in place of itraconazole oral solution (liquid) if that is what your doctor has prescribed. Avoid medication errors by using only the form and strength your doctor prescribes.
If you also take a stomach acid reducer (Tagamet, Pepcid, Axid, Zantac, and others), take Itraconazole with an acidic drink such as non-diet cola.
Use this medicine for the full prescribed length of time, even if your symptoms quickly improve. Skipping doses can increase your risk of infection that is resistant to medication. Itraconazole will not treat a viral infection such as the flu or a common cold.
You may need frequent medical tests.
Store at room temperature away from moisture, heat, and light.
What should I avoid while taking Itraconazole?
Avoid driving or hazardous activity until you know how this medicine will affect you. Your reactions could be impaired.
Avoid taking antacids within 1 hour before or 2 hours after you take Itraconazole. Some antacids can make it harder for your body to absorb itraconazole.
Itraconazole side effects
Get emergency medical help if you have signs of an allergic reaction to Itraconazole: hives, severe skin rash, tingling in your arms or legs; difficult breathing; swelling of your face, lips, tongue, or throat.
Stop using this medicine and call your doctor at once if you have signs of congestive heart failure: feeling tired or short of breath, cough with mucus, fast heartbeats, swelling, rapid weight gain, or sleep problems.
Keep taking Itraconazole but call your doctor at once if you have:
- confusion, a light-headed feeling (like you might pass out);
- blurred vision, double vision, ringing in your ears, problems with hearing;
- fast heartbeats;
- numbness or tingly feeling, loss of bladder control;
- little or no urinating, pain or burning when you urinate;
- low potassium level – leg cramps, constipation, irregular heartbeats, fluttering in your chest, increased thirst or urination, muscle weakness or limp feeling;
- pancreatitis – severe pain in your upper stomach spreading to your back, nausea and vomiting; or
- liver problems – nausea, upper stomach pain, tiredness, loss of appetite, dark urine, clay-colored stools, jaundice (yellowing of the skin or eyes).
- Common Itraconazole side effects may include:
- headache, dizziness, drowsiness, tiredness;
- increased blood pressure;
- rash, itching;
- nausea, vomiting, stomach pain, diarrhea, constipation;
- abnormal liver function or blood tests;
- fever, muscle or joint pain;
- unusual or unpleasant taste in your mouth;
- hair loss;
- impotence, erection problems; or
- changes in your menstrual periods.
What other drugs will affect Itraconazole?
Sometimes it is not safe to use certain medications at the same time. Some drugs can affect your blood levels of other drugs you take, which may increase side effects or make the medications less effective.
Many drugs can interact with itraconazole, and some drugs should not be used at the same time. Tell your doctor about all your current medicines and any medicine you start or stop using. This includes prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible interactions are listed here.