Drug Class: What is Mevacor an why is it prescribed?
Mevacor Mechanism: How does Mevacor work?
Mevacor Dosage: How should you take Mevacor
Possible food and drug interactions when taking Mevacor
Special information on Mevacor
Mevacor side effects
|Drug Class: What is Mevacor an why is it prescribed?|
|Mevacor is an HMG CoA reductase inhibitor. Lovastatin blocks the production of cholesterol (a type of fat) in the body.
Mevacor is used, along with diet changes (restriction of cholesterol and fat intake), to lower cholesterol levels in people with primary hypercholesterolemia (too much cholesterol in the bloodstream).
Mevacor is used to reduce the amounts of LDL (bad) cholesterol and total cholesterol in the blood. This is important in the prevention of heart disease and hardening of the arteries, which can lead to heart attack, stroke, and peripheral vascular disease.
|Mevacor Mechanism: How does Mevacor work?|
|Mevacor works by inhibiting the rate at which cholesterol is formed in the body.
Mevacor blocks the synthesis of cholesterol in the liver. In turn, the liver must acquire its cholesterol from the blood stream. Mevacor does so mainly in the form of LDL. Mevacor makes this possible by increasing LDL receptors. Mevacor also may help draw cholesterol to the liver for excretion.
Mevacor lowers overall blood cholesterol as well as blood LDL cholesterol levels. LDL cholesterol is believed to be the \"bad\" cholesterol that is primarily responsible for the development of coronary artery disease. Lowering LDL cholesterol levels retards progression and may even reverse coronary artery disease.
|Mevacor Dosage: How should you take Mevacor|
|Grapefruit and grapefruit juice may interact with Mevacor. The interaction could lead to potentially dangerous effects. Discuss the use of grapefruit and grapefruit juice with your doctor. Do not increase or decrease the amount of grapefruit products in your diet without first talking to your doctor.
Mevacor should be taken with meals.
Take each dose of Mevacor with a full glass of water.
Your doctor may want to monitor your liver function with blood tests before starting treatment with Mevacor, at six and twelve weeks after both the start of your treatment and any increase in dose, and periodically (every 6 months) thereafter. Depending on the results of these tests, your doctor can determine how much monitoring you will require Eat a low-fat, low-cholesterol diet. To see beneficial effects from Mevacor, avoid fatty, high-cholesterol foods.
If you miss a Mevacor dose
If you are taking Lopid, Atromid-S, Tricor or nicotinic acid in combination with Mevacor, your dose of Mevacor should not exceed 20 milligrams per day.
Cholesterol levels should be monitored periodically and consideration should be given to reducing the dosage of Mevacor if cholesterol levels fall below the targeted range.
In patients taking immunosuppressive drugs concomitantly with Mevacor, therapy should begin with 10 mg of Mevacor and should not exceed 20 mg/day.
If you have reduced kidney function, your doctor will be cautious about increasing your dosage of Mevacor.
Mevacor Storage instructions
Mevacor Preparations Tablets: 10mg, 20mg
|Possible food and drug interactions when taking Mevacor|
Mevacor tends to enhance the blood-thinning effect of Coumadin. In rare instances, Mevacor can also cause muscle pain and potential kidney damage when combined with the following:
If you are taking Mevacor with any of these drugs, (or with large quantities of grapefruit juice), alert your doctor immediately at the first sign of muscle pain, tenderness, or weakness, especially if accompanied by fever or general body discomfort. If you need to take erythromycin, Biaxin, Nizoral, or Sporanox, the doctor may temporarily take you off Mevacor.
Drugs other than those listed here may also interact with Mevacor. Talk to your doctor and pharmacist before taking any prescription or over-the-counter medicines, including vitamins, minerals, and herbal products.
|Special information on Mevacor|
|Most important fact about Mevacor
Mevacor is usually prescribed only if diet, exercise, and weight-loss fail to bring your cholesterol levels under control. It\'s important to remember that Mevacor is a supplement--not a substitute--for these other measures. To get the full benefit of Mevacor, you need to stick to the diet and exercise program prescribed by your doctor.
Special precautions if you are pregnant or breastdeeding
Mevacor may appear in breast milk and may have an effect on nursing infants. Do not take Mevacor without first talking to your doctor if you are breast-feeding a baby.
Special warnings about Mevacor
If you are being treated for any disease that contributes to increased blood cholesterol, such as hypothyroidism, diabetes, nephrotic syndrome (kidney and blood vessel disorder), dysproteinemia (an excess of protein in the blood), or liver disease, your doctor will closely monitor your reaction to Mevacor.
Alcohol and Mevacor can both be damaging to the liver. Alcohol should be used only in moderation. Discuss the use of alcohol with your doctor so that the potential for liver problems can be determined.
If you are planning to have elective surgery, Mevacor should be discontinued a few days before the operation. Mevacor should be used with caution if you consume substantial quantities of alcohol or have a past history of liver disease.
Why Mevacor should not be prescribed?
Unless you are directed to do so by your doctor, do not take Mevacor if you are being treated for liver disease.
Do not take Mevacor if you are pregnant or nursing.
|Mevacor side effects|
|Mevacor is generally well tolerated. Any side effects that have occurred have usually been mild and short-lived. If any side effects develop or change in intensity, inform your doctor as soon as possible. Only your doctor can determine if it is safe for you to continue taking Mevacor.
More common side effects of Mevacor may include:
Less common side effects of Mevacor may include:
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