Therapeutic response to a given dosage varies between patients, therefore, dosage must be individually titrated and should be carefully monitored. In the treatment of hypertension, Generic Inderal may be started by administering the drug in 2 equal daily doses of 40 mg. This may be increased, if necessary, in one week, to 80 mg twice daily, before breakfast and at bedtime. If necessary, the drug may be increased to 160 mg twice daily. For most patients the dosage is within the range of 160 to 320 mg daily. A small number of patients may respond to 80 mg daily. Experience to date suggests that in some resistant patients increasing the dosage above 320 mg/day may have an additional effect. Doses above 320 mg/day should be given on a 3 or 4 times daily regimen.
The time course of full blood pressure response is variable. The antihypertensive effect will usually occur within 3 to 7 days after reaching the effective dose. The maximum decrease in blood pressure may occur 2 to 4 weeks after initiation of treatment.
Dosage must be individualized. Initiate therapy with 20 to 40 mg twice daily before meals. If satisfactory response is not obtained after 1 week, dosage should be increased to 80 mg twice daily. Although individual patients may respond to any dosage level, the average optimum dosage of Generic Inderal appears to be 160 mg/day. Occasionally in resistant patients dosages as high as 320 to 400 mg/day have been administered with beneficial results. If treatment is to be discontinued, reduce Generic Inderal dosage gradually over a period of about 2 weeks.
10 to 30 mg 3 or 4 times daily, before meals and at bedtime.
Initiate therapy with a 20 mg dose. If no adverse reaction is noted, increase the dose of Generic Inderal to 40 mg three times daily. After one to two weeks increase the dose of Generic Inderal to 60 mg three time daily. If necessary, the dose may be increased to 80 mg three times daily. In a large study involving 3837 patients, this larger dose was used in approximately 20% of patients.
Dosage must be individualized. The initial dose of Generic Inderal is 40 mg twice daily. The dose may then be gradually increased until optimum migraine prophylaxis is achieved. The usual effective dose range is 80 to 160 mg/day.
Hypertrophic Subaortic Stenosis:
20 to 40 mg, 3 or 4 times daily, before meals and at bedtime.
Individualize dosage. The initial dose is 80 mg daily in divided doses. The dosage of Generic Inderal may be increased to 120 to 160 mg daily for optimal effects. If a patient does not respond to the drug within this dosage range, it is unlikely that further increases in dosage will produce a therapeutic effect, although a few patients have benefited from a daily dose of 240 mg. In elderly patients, doses above 120 mg daily may increase the risk of side effects such as bradycardia, syncope and bronchospasm.
Preoperatively: 60 mg daily, in divided doses, for 3 days before surgery, concomitantly with an alpha-receptor blocking agent. Malignant cases: 30 mg daily, in divided doses.
Generic Inderal Overdose:
No specific information on Generic Inderal overdose is available; however, overdose symptoms with other beta blockers include:
- extremely slow heartbeat,
- irregular heartbeat,
- low blood pressure,
- severe congestive heart failure,
If you miss a dose of Generic Inderal:
Take it as soon as you remember. If it is near the time for the next dose, skip the missed dose and resume your regular dosage schedule. Do not double the next dose.
Generic Inderal Storage instructions:
Keep your Generic Inderal tablets in the bottle until it is time to take them. If you take Generic Inderal out of the bottle it will not keep well.
Keep it in a cool dry place where the temperature stays below 30ºC.
Do not store Generic Inderal in the bathroom or near a sink. Heat and dampness can destroy Generic Inderal.
Keep Generic Inderal where young children cannot reach it. A locked cupboard at least one-and-a-half metres above the ground is a good place to store medicines.
Do not leave Generic Inderal in the car on hot days.
Generic Inderal Disposal
Ask your pharmacist what to do with any tablets you have left over if your doctor tells you to stop taking them, or you find that the expiry date has passed.
Generic Inderal Preparations: Generic Inderal 10 mg, Generic Inderal 40 mg, Generic Inderal 80 mg.